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International Journal of Hematology-Oncology and Stem Cell Research، جلد ۱۲، شماره ۱، صفحات ۶۹-۷۶
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عنوان انگلیسی Predictors and Correlates of Fatigue in Sickle Cell Disease Patients
چکیده انگلیسی مقاله Background: Although fatigue is the most important symptom of Sickle Cell Disease, the extent of it is unknown, and causal mechanisms are not well understood. This article explores biopsychosocial characteristics that can potentially contribute to fatigue in SCD. Materials and Methods: This cross-sectional, correlational study included 97 SCD patients who aged over 16 years and had records in Thalassemia Ward and Clinic of Shafa Hospital affiliated to Ahvaz University of Medical Sciences, Ahvaz, Iran. Data were collected from a self- reported demographic questionnaire, measuring depression, anxiety stress scale (DASS-21) and fatigue severity scale (FSS). Data analysis was done by descriptive statistics, independent sample t-tests, Pearson's correlation coefficient, one-way ANOVA and multiple stepwise regression. Results: More than 50% of study participants were mostly single women. A majority of patients had a diagnosis of HgbSS disease. Levels of depression, anxiety and stress were severe in more than half of the participants. About 65% of SCD patients reported signs of fatigue. Moreover, fatigue, depression, anxiety and stress had a high intercorrelation. Depression, blood transfusion, renal diseases and work status were predictors of fatigue according to the models used in this survey. Conclusion: The results of the study indicated that SCD patients who had depression, blood transfusions, SCD-related renal complications, students and working people experienced more fatigue. So, if fatigue is present, it is important to recognize the existence of these conditions or vice versa. Routine assessment and improved management of fatigue, effective interventions to reduce fatigue, are highly recommended for patients with SCD.
کلیدواژه‌های انگلیسی مقاله Anxiety, Depression, Stress, Fatigue, Sickle cell disease
نویسندگان مقاله مهرناز احمدی | mehrnaz ahmadi
treatment deputy, ahvaz jundishapur university of medical sciences, ahvaz, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی جندی شاپور اهواز (Ahvaz jundishapur university of medical sciences)

سعید پورمنصوری | saeed poormansouri
department of nursing, student research committee, school of nursing and midwifery, ahvaz jundishapur university of medical sciences, ahvaz, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی جندی شاپور اهواز (Ahvaz jundishapur university of medical sciences)

سمیرا بیرانوند | samira beiranvand
department of nursing, student research committee, school of nursing and midwifery, shahid beheshti university of medical sciences, tehran, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی شهید بهشتی (Shahid beheshti university of medical sciences)

لادن صدیقی | ladan sedighie


نشانی اینترنتی http://ijhoscr.tums.ac.ir/index.php/ijhoscr/article/view/690
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زبان مقاله منتشر شده en
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نوع مقاله منتشر شده Original Article(s)
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