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Medical Journal of Islamic Republic of Iran، جلد ۲۵، شماره ۱، صفحات ۱۶-۲۰
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عنوان انگلیسی Lead toxicity: a probable cause of abdominal pain in drug abusers
چکیده انگلیسی مقاله Abstract Background: Lead toxicity is caused by ingestion, inhalation, or contact with particles or vapors containing lead. It can present with nonspecific signs and symptoms such as abdominal pain, constipation, irritability, difficulty concentrating, and anemia. In this study, we have tried to find a relationship between lead poisoning and drug abuse. Methods: In a cross sectional study, drug addicts presenting with abdominal pain referring to GI center of Imam Khomeini hospital in 2008 were observed. Patients having occupational contact with lead were excluded from the study. Required data included age, sex, clinical findings, Para clinic results and blood lead level. Results were analyzed through SPSS-15 software. Results: 42 patients (all male) with average age of 46.9 ± 10.1 years were included in the study. Average blood lead level was 51.17±27.96µg/dl. 22 patients (52.6%) had lead toxicity. A significant relation was found between lead toxicity and mode of opium drug use however relation between lead toxicity and duration of addiction was not significant. Similarly, a meaningful relation was found between lead toxicity and abnormal liver function test, urine tests, ECG, presence of basophilic stippling and hyperuricemia. Conclusion: There seems to be a significant relation between opium drug abuse and lead toxicity. Further studies with more cases and ethnicities are needed.
کلیدواژه‌های انگلیسی مقاله Lead toxicity, opium, drug abusers, abdominal pain
نویسندگان مقاله حسین فروتن | hossein froutan
department of gastroenterology, imam khomeini hospital, tehran university of medical sciences. tehran; iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)
سازمان های دیگر: Imam Khomeini Hospital

علیرضا کاشفی زاده | alireza kashefi zadeh
department of gastroenterology, imam khomeini hospital, keshavarz blv. tehran, iran

سازمان های دیگر: Imam Khomeini Hospital

محمد کلانی | mohammad kalani
department of gastroenterology, imam khomeini hospital, keshavarz blv. tehran, iran

سازمان های دیگر: Imam Khomeini Hospital

yasir andrabi | yasir andrabi
department of gastroenterology, imam khomeini hospital, keshavarz blv, tehran, iran

سازمان های دیگر: Imam Khomeini Hospital

نشانی اینترنتی http://mjiri.iums.ac.ir/browse.php?a_code=A-10-1-139&slc_lang=en&sid=en
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