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Physiology and Pharmacology، جلد ۲۱، شماره ۴، صفحات ۳۴۳-۳۵۰
عنوان فارسی
چکیده فارسی مقاله
کلیدواژه‌های فارسی مقاله
عنوان انگلیسی Effect of Syzygium aromaticum (clove) extract on seminiferous tubules and oxidative stress after testicular torsion in adult rats
چکیده انگلیسی مقاله Introduction: The aim was to investigate the protective effect of the Syzygium aromaticum extract on damaged tissues and the oxidative stress after testicular torsion. Methods: Rats were randomly divided into a control group subjected to a sham procedure and three treatment groups comprising testicular torsion followed by detorsion (TD), testicular torsion detorsion followed by the treatment with an extract of Syzygium aromaticum (TDSA) and treatment done by extract of Syzygium aromaticum alone. Testicular torsion was induced by 720 degrees of counterclockwise rotation of the left testis for 4h. After the duration of the induction of the torsion, detorsion was done. The animals were given daily oral administrations of just Syzygium aromaticum (4 mg/kg) for seven days. The measurement of the oxidative stress and testosterone levels, as well as assessments of histomorphometry were conducted seven days after detorsion. Results: The Johnsen score, along with the thickness of the epithelium and diameter of the seminiferous tubules, significantly increased in the testicular torsion group after receiving treatment with the extract of Syzygium aromaticum as compared to TD group. The levels of testosterone and glutathione peroxidase activity also increased significantly in the TDSA compared to TD group. The MDA levels decreased in TDSA compared to TD group. Conclusion: The findings of the current study suggested that Syzygium aromaticum might have provided a protective effect against testicular torsion detorsion injury.
کلیدواژه‌های انگلیسی مقاله
نویسندگان مقاله مریم مقیمیان | maryam moghimian
department of basic sciences, school of medicine, gonabad university of medical sciences, gonabad, islamic republic of iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی گناباد (Gonabad university of medical sciences)

سید حسین ابطحی ایوری | seyd hosein abtahi evari
department of basic sciences, school of medicine, gonabad university of medical sciences, gonabad, islamic republic of iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی گناباد (Gonabad university of medical sciences)

مجید شکوهی | majid shokoohi
department of basic sciences, school of medicine, gonabad university of medical sciences, gonabad, islamic republic of iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی گناباد (Gonabad university of medical sciences)

مصطفی امیری | mostafa amiri
department of basic sciences, school of medicine, gonabad university of medical sciences, gonabad, islamic republic of iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی گناباد (Gonabad university of medical sciences)

ملیحه سلطانی | malihe soltani
department of basic sciences, school of medicine, gonabad university of medical sciences, gonabad, islamic republic of iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی گناباد (Gonabad university of medical sciences)

نشانی اینترنتی http://phypha.ir/ppj/browse.php?a_code=A-10-988-1&slc_lang=en&sid=en
فایل مقاله اشکال در دسترسی به فایل - ./files/site1/rds_journals/26/article-26-568092.pdf
کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده Others
نوع مقاله منتشر شده Original Research
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