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JCR 2016
جستجوی مقالات
شنبه 25 بهمن 1404
International Journal of Pediatrics
، جلد ۶، شماره ۹، صفحات ۸۲۳۳-۸۲۳۹
عنوان فارسی
چکیده فارسی مقاله
کلیدواژههای فارسی مقاله
عنوان انگلیسی
Exploring Vitamin D in Children with Febrile Seizure: A Preliminary Study
چکیده انگلیسی مقاله
Background: Febrile seizures are the most common convulsive disorder in children. There is growing evidence that vitamin D can affect gene expression and modulate various cell metabolisms. Also vitamin D may have a role in the etiology of febrile seizures. We aimed to explore vitamin D status in children with febrile seizure. Materials and Methods: This cross-sectional study was conducted on 40 children with first episode of febrile seizure referring to Children's Medical Center in Tehran, Iran. A 5 ml blood sample was taken from the peripheral veins of each participant. Serum levels of vitamin D, calcium, phosphorus, parathyroid hormone (PTH), and alkaline phosphates (ALP) was recorded. Other variables that were recorded from each case were gender, age, parental consanguinity and family history of febrile seizure. Patients' skin color was categorized based on Fitzpatrick's scale. We asked the parents to complete a validated food frequency questionnaire including vitamin D sources in children. Results: The mean plasma calcium, phosphorous, PTH and ALP were in normal ranges; the mean vitamin D level was 24.41±11.21 ng/ml) in insufficient range). In 7.5% of patients, vitamin D level was in the deficient, 72.5% was in the insufficient and 20% was in sufficient levels. There was no significant difference in vitamin D level between two sexes (P=0.85). There was no significant correlation between vitamin D level and age (P=0.34). There was no significant correlation between vitamin D level and its metabolites (P>0.05). Conclusion There was a high prevalence of vitamin D insufficiency among ourpatients with febrile seizure. Further analytical studies are recommended to prove the relation between vitamin D deficiency and febrile seizure.
کلیدواژههای انگلیسی مقاله
Children, Febrile seizure, Iran, Vitamin D
نویسندگان مقاله
| Ghazal Shariatpanahi
Ziaeian Hospital, Pediatric Department, International Campus, Tehran University of Medical Sciences, Tehran, Iran.
| Nobar Paprooschi
Pediatric Department, International Campus, Tehran University of Medical Sciences, Tehran, Iran.
| Bahareh Yaghmaei
Pediatric Intensifier, Children's Medical Center, Pediatrics Center of Excellence, Tehran University of Medical Sciences, Tehran, Iran.
| Fatemeh Sayarifard
Growth and Development Research Center, Children`s Medical Center, Pediatrics Center of Excellence, International Campus, Tehran University of Medical Sciences, Tehran, Iran.
| Azadeh Sayarifard
Growth and Development Research Center, Community Based Participatory Research Center, Iranian Institute for Reduction of High - Risk Behaviors, Tehran University of Medical Sciences, Tehran , Iran.
نشانی اینترنتی
http://ijp.mums.ac.ir/article_10506.html
فایل مقاله
اشکال در دسترسی به فایل - ./files/site1/rds_journals/317/article-317-639554.pdf
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