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Medical Journal of Islamic Republic of Iran، جلد ۲۲، شماره ۳، صفحات ۱۳۷-۱۴۰

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عنوان انگلیسی Fungal infection of the sinus and anterior skull base
چکیده انگلیسی مقاله Abstract Background: Invasive fungal infection is an opportunistic infection caused commonly by mucoraccae and aspergillus. It mostly occurs in patients with underlying disease. Since it has a high mortality and morbidity rate, considering a treatment strategy seems necessary. Objective: Since there has not been a clear protocol for treating these patients, we decided to establish a protocol for fungal infection of sinus and anterior skull base management. Methods: This retrospective and descriptive case study series included 30 patients. After confirming the pathogen, the authors came to a proper protocol for treatment which is mentioned later. Results: The site involvement included nose and orbital cavity (53.3%), anterior skull base and brain in conjunction with sinonasal (36.6%) and simple nasal cavity involvement (10%). 86.6% of the patients had underlying diseases. 56.6% of patients had diabetes as a single underlying disease, while 13.3% had both diabetes and renal failure in combination. Acute lymphocytic leukemia was present in 6.6%, renal failure in 3.3%, lupus in 3.3% and chronic lymphocytic leukemia in 3.3% of patients. Mortality rate was 40%. We categorized the patients into 3 groups: only sinonasal, sinonasal and orbit, and associated anterior skull base and brain involvement. Conclusion: Early diagnosis is an important factor in improving survival. Anterior skull base and brain involvement has a very poor prognosis.
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نویسندگان مقاله مرتضی جوادی | morteza javadi
head amp; neck surgery, hazrat-e rasoul akram hospital, iran university of medical sciences,

سازمان اصلی تایید شده: دانشگاه علوم پزشکی ایران (Iran university of medical sciences)

شباهنگ محمدی | shabahang mohammadi
head neck surgery, department research center of ent and head neck surgery iums , hazrat-e rasoul akram hospital,

سازمان های دیگر: Research Center of ENT and Head &


نشانی اینترنتی http://mjiri.iums.ac.ir/browse.php?a_code=A-10-1-5&slc_lang=en&sid=en
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