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International Journal of Hematology-Oncology and Stem Cell Research، جلد ۱۲، شماره ۳، صفحات ۲۳۴-۲۴۷
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عنوان انگلیسی Liquid Biopsy in Thyroid Cancer: New Insight
چکیده انگلیسی مقاله Thyroid cancer, one of the most widespread malignancies of the endocrine-related system that over the past three decades, has a vivid increasing rate. The diagnosis and management of it is dependent on the tumor type and stage. Thyroid cancer is divided into four main types, including PTC (papillary thyroid carcinoma), FTC (follicular thyroid carcinoma), MTC (medullarly thyroid carcinoma), and ATC (anaplastic thyroid carcinoma). The development of the noninvasive diagnostic tool for plasma genotyping, also known as “liquid biopsy”, brings a new insight for cancer diagnosis and prognosis. It is mainly containing circulating tumor DNA (ctDNA), circulating tumor cell (CTC), exosomes and extrachromosomal circular DNA (ecDNA). Liquid biopsy as a new plasma genotyping source brings a new prospective of tumor monitoring and therapy. It beneficially reduces the need of tissue biopsy and made early recognition of relapse as well. This article summarizes its components characteristics and their benefit in diagnosis and treatment of thyroid cancer.
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نویسندگان مقاله | Fatemeh Khatami
Department of Pathology, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran


| Seyed Mohammad Tavangar


نشانی اینترنتی http://ijhoscr.tums.ac.ir/index.php/ijhoscr/article/view/926
فایل مقاله اشکال در دسترسی به فایل - ./files/site1/rds_journals/78/article-78-694639.pdf
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زبان مقاله منتشر شده en
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نوع مقاله منتشر شده Review Article(s)
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