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Iranian Journal of Toxicology، جلد ۱۰، شماره ۵، صفحات ۷-۱۰
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عنوان انگلیسی Characterization and Pharmacological Activities of Jellyfish, Chrysaora hysoscella Captured in Bushehr Port, Iran
چکیده انگلیسی مقاله Background: Cutaneous reactions like pruritus and erythema are common in warm months of the year in Bushehr Port, Persian Gulf, Iran due to jellyfish envenomation. This study reports isolation of the Chrysaora hysoscella nematocysts and evaluating its pharmacological activities during a bloom in 2013. Methods: The venom of C. hysoscella captured in Jofre area in Bushehr port was analyzed. The electrophoretic profile was assessed by SDS-PAGE (12.5%) and the crude sample was analyzed using reverse phase HPLC. Caseinase activity was also determined. Results: After separation of tentacles and isolation of their nematocysts, three different major protein components were revealed at 72-250 kDa with SDS-PAGE, signifying the presence of peptides in its venom. Two major peaks at 8.62 and 11.23 min were observed in reverse phase HPLC of the crude venom denoting protease peptide structural identities. Caseinase activity of C. hysoscella's venom was extremely low as compared with other jellyfish venoms. Conclusion: This was the first report on the structural examination of jellyfish in Persian Gulf and may pave the way for determination and separation of destructive enzymes inducing cutaneous reactions in fishermen and swimmers.
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نویسندگان مقاله سمیه غریبی | somayyeh gharibi
department of marine toxicology, the persian gulf marine biotechnology research center, bushehr university of medical sciences, bushehr, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی بوشهر (Bushehr university of medical sciences)

ایرج نبی پور | iraj nabipour
department of marine toxicology, the persian gulf marine biotechnology research center, bushehr university of medical sciences, bushehr, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی بوشهر (Bushehr university of medical sciences)

euikyung کیم | euikyung kim
phd of toxicology, college of veterinary medicine, gyeoungsang national university, jinju, south korea.


سیده مریم غفاری | seyede maryam ghafari
department of parasitology, pasteur institute, tehran, iran.

سازمان اصلی تایید شده: انستیتو پاستور ایران (Pasteur institute of iran)

سید مهدی حسینی | seyed mehdi hoseiny
department of marine toxicology, the persian gulf marine biotechnology research center, bushehr university of medical science


مصطفی کامیاب | mostafa kamyab
department of biological sciences, shahid beheshti university, tehran, iran.

سازمان اصلی تایید شده: دانشگاه شهید بهشتی (Shahid beheshti university)

رامین سیدیان | ramin seyedian
department of marine toxicology, the persian gulf marine biotechnology research center, bushehr university of medical sciences, bushehr, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی بوشهر (Bushehr university of medical sciences)

نشانی اینترنتی http://ijt.arakmu.ac.ir/browse.php?a_code=A-10-76-1&slc_lang=en&sid=en
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