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Iranian Journal of Kidney Diseases، جلد ۱۲، شماره ۴، صفحات ۲۴۳-۰
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عنوان انگلیسی Immunoglobulin G4-related Kidney Disease Associated With Autoimmune Hemolytic Anemia
چکیده انگلیسی مقاله Awareness of the uncommon associated clinical manifestations of immunoglobulin G4 (IgG4)-related kidney disease is essential for the early diagnosis and effective treatment of patients. To the best of our knowledge, there have been few reports of patients with IgG4-related kidney disease associated with autoimmune hemolytic anemia. We here report a rare case of IgG4-related kidney disease associated with autoimmune hemolytic anemia. A 70-year-old man with kidney dysfunction and severe anemia had been diagnosed with chronic kidney disease and treated without any improvement. On admission, he had a high serum creatinine level, low hemoglobin level, positive direct Coombs test, and mild proteinuria. Serum IgG and IgG4 were elevated. Kidney biopsy showed marked infiltration of IgG4-positive plasma cells and storiform fibrosis in the interstitial compartment, which confirmed the diagnosis of IgG4-related kidney disease. Corticosteroid therapy was initiated, and subsequently, the kidney dysfunction and anemia dramatically improved.
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نویسندگان مقاله | Shen-Ju Gou


| Shao-Bin Yu


| Hong-Yu Qiu


| Zhang-Xue Hu


نشانی اینترنتی http://ijkd.org/index.php/ijkd/article/view/3685
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نوع مقاله منتشر شده CASE REPORT | Kidney Diseases
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