این سایت در حال حاضر پشتیبانی نمی شود و امکان دارد داده های نشریات بروز نباشند
Medical Journal of Islamic Republic of Iran، جلد ۱۷، شماره ۳، صفحات ۱۸۹-۱۹۲
عنوان فارسی
چکیده فارسی مقاله
کلیدواژه‌های فارسی مقاله
عنوان انگلیسی A STUDY OF MYCOBACTERIUM TUBERCULOSIS DRUG RESISTANCE IN PULMONARY TUBERCULOSIS
چکیده انگلیسی مقاله Tuberculosis remains a major public health problem in both developing and developed countries. Drug-resistant tuberculosis is an increasing health problem and serious challenge to tuberculosis (TB) control programs. Information about the susceptibility pattern of Mycobacterium tuberculosis isolates against anti-tuberculosis drugs is an important aspect to TB control. The objectives of the study were to evaluate the frequency of drug-resistance and to survey the nature of drug resistance among patients with pulmonary tuberculosis. Ninety-one M. tuberculosis strains were isolated from sputum samples of patients referred to Cerrhapasa Medical Faculty Hospital, Istanbul, Turkey, during a 9 month period. Drug susceptibility testing was performed to isoniazid (INH), streptomycin (SM), ethambutol (EMB) and rifampin (RMP) on Lowenstein-Jensen medium according to proportion method. Total resistance was identified in 40 of 91 patients (44%). The highest rate of primary resistance was to SM (21.1 %), followed by INH (15.8%), RMP (5.3%) and EMB (2.6%). Secondary resistance was most frequent to INH (33.3%), followed by SM (28.6%), RMP (23.8%) and EMB (14.3%). Multidrug resistance (MDR) was observed in 6 of the 91 cases (6.6%). Due to the high prevalence of drug resistance, particularly in developing countries, further studies should be conducted regularly to monitor resistance in these countries.
کلیدواژه‌های انگلیسی مقاله
نویسندگان مقاله sr مودب | sr moaddab
from thedepartment of clinical microbiology, istanbul university, istanbul, turkey


a رفیع | a rafi
theresearch center for tb and pulmonary diseases, tabriz university of medical sciences, tabriz, iran.

سازمان اصلی تایید شده: 0 دانشگاه های خارج از کشور

نشانی اینترنتی http://mjiri.iums.ac.ir/browse.php?a_code=A-10-298-138&slc_lang=en&sid=en
فایل مقاله فایلی برای مقاله ذخیره نشده است
کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده
نوع مقاله منتشر شده 1
برگشت به: صفحه اول پایگاه   |   نسخه مرتبط   |   نشریه مرتبط   |   فهرست نشریات