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Journal of Research in Medical Sciences، جلد ۲۱، شماره ۷، صفحات ۰-۰
عنوان فارسی
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عنوان انگلیسی The role of magnesium sulfate in tracheal intubation without muscle relaxation in patients undergoing ophthalmic surgery
چکیده انگلیسی مقاله Background: Muscle relaxant agents usually use to facilitate tracheal intubation; however, sometimes limitations exist. Magnesium (Mg) sulfate is a candidate for muscle relaxant substitute. This study was designed to determine the effect of Mg sulfate accompanied with propofol and fentanyl in patients undergoing ophthalmic surgery. Materials and Methods: In a double?blind randomized protocol and before tracheal intubation, Mg sulfate 40, 45, or 50 mg/kg in 100 ml of saline (Groups 1–3, respectively) or saline alone (Group 4) were administrated intravenously in 100 patients (n = 25 in each group) with the American Society of Anesthesiologist (ASA) physical Status I, II, or III. The patients’ intubation condition in all subjects were determined and described. Results: The patients’ demographic data including age, ASA, systolic and diastolic blood pressures, intraocular pressure, and body mass index were not significantly different between the groups. A better mask ventilation feasibility in Mg sulfate 45 group (Group 2) was observed when compared with Mg sulfate 50 (Group 3) (P = 0.022) and saline group (Group 4) (P = 0.021). In addition, the vocal cord movement and muscle relaxant requirement in saline group were significantly different from others groups (P < 0.05). The laryngoscopic time in saline group was greater than other groups significantly (P < 0.0001). Conclusion: Intravenous administration of Mg sulfate accompanied with propofol and fentanyl facilitates the tracheal intubation without neuromuscular blocking agents. To avoid Mg level increasing in plasma; however, the low dose of Mg sulfate is suggested.
کلیدواژه‌های انگلیسی مقاله Anesthesia, magnesium sulfate, tracheal intubation
نویسندگان مقاله حسن علی سلطانی | hassan ali soltani


سید جلال هاشمی | seyed jalal hashemi


کامران منتظری | kamran montazeri


علیرضا دهقانی | alireza dehghani


مهدی نعمت بخش | mehdi nematbakhsh


نشانی اینترنتی http://jrms.mui.ac.ir/index.php/jrms/article/view/10519
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زبان مقاله منتشر شده en
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نوع مقاله منتشر شده Original Articles
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